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Real Time and Accelerated Stability Studies of Testosterone Calibrators
Authors: Linda Nagore, Ravi Orugunty, Isil Dilek, and Uma Sreenivasan
Presented at American Society for Mass Spectrometry (ASMS), San Antonio, TX, June 5-9, 2016
Potency Claims - only as Accurate as your Reference Material. Challenges with unstable THC and related Cannabinoids
Authors: Mitzi Rettinger
Presented at The Emerald Conference, Las Vegas, NV, January 21-22, 2016
Impact of isomeric differences between internal standard and analyte for the LC-MS/MS quantification of 11-Nor-delta9-THC-9-carboxylic acid glucuronide
Authors: Sarah Aijaz, Alexander Wong, Isil Dilek, and Uma Sreenivasan
Presented at The American Society for Mass Spectrometry (ASMS), St. Louis, MO, May 31-June 4, 2015
Selection of Internal Standards for LC-MS/MS Applications
Authors: Uma Sreenivasan, Isil Dilek, Josh Cooper, Sarah Aijaz, Ravi Orugunty, Derrell Johnson, Heather Lima, Mitzi Rettinger
Presented at Mass Spectrometry Applications to the Clinical Lab (MSACL), San Diego, CA, March 28-April 1, 2015
Design and Synthesis of Labeled 2C-B-FLY and Bromo-DragonFLY for Internal Standards Used in Forensic/Clinical Toxicology Analysis
Authors: Heather Lima, Uma Sreenivasan, Kenan Yaser
Presented at American Chemical Society (ACS), Dallas, TX, March 16-20, 2014
Regioselective Friedel-Crafts Type Acylation of Indoles: An Improvement on the Synthesis of Cannabimimetic Indole Metabolites
Authors: Lindsey Hess, Uma Sreenivasan, Kenan Yaser
Presented at American Chemical Society (ACS), Dallas, TX, March 16-20, 2014
Synthetic and Analytical Challenges of Retigabine and N-Acetyl Retigabine
Authors: Heather Lima, Uma Sreenivasan, Isil Dilek, Josh Cooper, Brian Dockery, and Genevieve Rodgers
Presented at Society of Forensic Toxicologists (SOFT), Orlando, FL, October 28-November 1, 2013
Analytical Reference Standards: Synthesis and Characterization of Cocaine N-oxide HCl
Authors: Yunming Ying, Brian Schulmeier, Uma Sreenivasan, Isil Dilek, Genevieve Rodgers, Sandra Ybarra
Presented at Society of Forensic Toxicologists (SOFT), Orlando, FL, October 28-November 1, 2013
Synthesis of JHW-250 4-hydroxypentyl Metabolite
Authors: Martha Liu, Kenan Yaser, Dillon Edwards and Uma Sreenivasan
Presented at 43rd National Organic Symposium Jun 23-27 at University of Washington, Seattle
Variables that Impact Immunosuppressant LC-MS/MS Analysis
Authors: Josh Cooper, Beth Marek, Isil Dilek, and Uma Sreenivasan
Presented at 61st American Society for Mass Spectrometry (ASMS) Conference, Minneapolis, MN, June 2013
Accurate Reference Standards for Accurate Quantitation of Thyroid Hormones: Impact on Clinical Reference Ranges
Authors: Beth Marek, Josh Cooper, Isil Dilek, Mitzi Rettinger, Greg Kirkovits, William Chen, Yunming Ying, Uma Sreenivasan, Matthew Crawford, Brett Holmquist, Russell P Grant
Presented at Mass Spectrometry Application to the Clinical Lab (MSACL), San Diego, CA, February 2013
Tadalafil: A Case Study for the Development of Stable Solution Reference Standards for Pharmaceutical Applications
Authors: Matthew Borer, Michael Julius, David Lytle, Tamara Tarbox, Isil Dilek, Uma Sreenivasan, Mitzi Rettinger
Presented at 11th International Symposium on Pharmaceutical Reference Standards, Strasbourg, France, September 2012
Solution Reference Standards for Protein Based Pharmaceuticals
Authors: Matthew Borer, Margaret McInerney, Kimberly Dancheck, David Lytle, Tamara Tarbox, Isil Dilek, Uma Sreenivasan, Mitzi Rettinger, Kevin Gates
Presented at 11th International Symposium on Pharmaceutical Reference Standards, Strasbourg, France, September 2012
Design and Development Challenges of Natural Products Certified Reference Solutions
Authors: Tamara Tarbox, Isil Dilek, Derrell Johnson, and Mitzi Rettinger
Presented at Association of Official Analytical Chemists (AOAC), Las Vegas, NV, October 2012
Challenges in the Development of Certified Vitamin Reference Solutions
Authors: Beth Marek, Derrell Johnson, Isil Dilek, Mitzi Rettinger
Presented at Association of Official Analytical Chemists (AOAC), Las Vegas, NV, October 2012
Accelerated Stability Studies by High Performance Liquid Chromatography
Authors: Greg Serna, Tamara Tarbox, Isil Dilek
Presented at Cerilliant - 2012 Sigma Aldrich® Summer Intern Program, Round Rock, TX, August 2012 
Analytical Challenges with MS Analysis of Bath Salts and Spice Cannabinoid Metabolites
Authors: Joshua Cooper, Ryan Carrell, Ning Chang, Yunming Ying, Greg Kirkovits, Derrell Johnson, Isil Dilek, Uma Sreenivasan
Presented at Society of Forensic Toxicologists (SOFT), Boston, MA, July 2012
±threo-Ritalinic acid-D10 Hydrochloride an internal standard for quantitation of Ritalinic acid by LCMSMS: Synthesis determination of isotopic distribution by qNMR and LCMS
Authors: Elizabeth B. Marek, Joshua Cooper, Huahua Jian, Uma Sreenivasan, Isil Dilek
Presented at Mass Spectrometry Application to the Clinical Lab (MSACL), San Diego, CA, January 2012
Evaluation of LCMSMS Deuterium Scrambling in Clinically Significant Small Molecules
Authors: Joshua Cooper, IsilDilek, UmaSreenivasan
Presented at Mass Spectrometry Application to the Clinical Lab (MSACL), San Diego, CA, January 2012
Improved GCMS Derivatization Techniques for Analysis of New Designer Drugs: Methylone, Ethylone, Butylone, Mephedrone, and Methedrone
Authors: Ryan Carrell, Isil Dilek, Ning Chang, Uma Sreenivasan, Yunming Ying, Greg Kirkovits
Presented at Society of Forensic Toxicologists (SOFT) / The International Association of Forensic Toxicologists (TIAFT), San Francisco, CA, September 2011
Certification of Reference Materials: Purity Analysis of Morphine-3β-D-Glucuronide by Quantitative NMR, Enzymatic Hydrolysis LC-MS/MS Assay, and Mass Balance Purity Factor
Authors: Huahua Jian, Martha Liu, Uma Sreenivasan and Isil Dilek
Presented at Society of Forensic Toxicologists (SOFT) / The International Association of Forensic Toxicologists (TIAFT), San Francisco, CA, September 2011
Analytical Reference Standards: Synthesis and Characterization of ±-threo-Ritalinic Acid-D10 Hydrochloride
Authors: Elizabeth B. Marek PhD, Huahua Jian PhD, Uma Sreenivasan PhD, Isil Dilek PhD
Presented at Society of Forensic Toxicologists (SOFT) / The International Association of Forensic Toxicologists (TIAFT), San Francisco, CA, September 2011
Everolimus-d4: An Internal Standard for Quantitation of Everolimus and Related Immunosuppressants by LCMS
Authors: Yunming Ying  PhD, Huahua Jian PhD, Isil Dilek PhD, Uma Sreenivasan PhD
Presented at Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock, TX 78665
Evaluation of LCMS/MS scrambling ratios for deuterium-labeled Vitamin D metabolites, steroids and other compounds of clinical significance
Authors: Joshua Cooper PhD, Huahua Jian PhD, Derrell Johnson, Isil Dilek PhD, and Uma Sreenivasan PhD
Presented at the American Association for Clinical Chemistry (AACC) Annual Meeting and Clinical Lab Expo, Atlanta, Ga, July 2011
Mitigation of Deuterium Scrambling in Stable-Labeled Internal Standards during LC-MS/MS Analysis
Authors: Joshua Cooper, Billy Molloy, Huahua Jian, Lisa Calton, Derrell Johnson, Isil Dilek, Uma Sreenivasan, Don Cooper
Presented at Mass Spectrometry Application to the Clinical Lab (MSACL), San Diego, CA, February 2011
High Quality, Certified Snap-N-Shoot Standards of Reb A & Stevia Impurities Ensure Accuracy & Consistency in Quantitative Applications
Authors: Mitzi Rettinger, Isil Dilek, PhD, Sandra Ybarra, Uma Sreenivasan, PhD, and Sherri Pogue
Presented at Association of Official Analytical Chemists (AOAC), Orlando, FL, September 2010
What Makes a Good Reference Standard
Authors: Mitzi Rettinger, Uma Sreenivasan, PhD, Isil Dilek, PhD, Sherri Pogue
Presented at Association of Official Analytical Chemists (AOAC), Orlando, FL, September 2010
Custom Certified Stock Solutions for Use in Manufacture of IVD Reagents or Controls
Authors: Mitzi Rettinger, Uma Sreenivasan, Isil Dilek, Sherri Pogue
Presented at American Association for Clinical Chemistry (Clinical Lab Expo) (AACC), Anaheim, CA, July 2010
Investigation of the Impurities in Dronabinol Samples by LCMS
Authors: Huahua Jian, Isil Dilek, Uma Sreenivasan, Kenan Yaser
Presented at Pittcon, Orlando, FL, March 2010
Measurement and Uncertainty of Residual Inorganic Content by Micro-ROI Analysis for Certification of Reference Materials
Authors: Ryan Carrell, HuaHua Jian, Kevin Gates, Isil Dilek, Uma Sreenivasan
Presented at Pittcon, Orlando, FL, March 2010
High Quality, Certified Snap-N-Shoot® Standards of Reb A and Stevia Impurities Ensure Accuracy and Consistency in Quantitative Applications
Authors: Mitzi Rettinger, Uma Sreenivassan, Isil Dilek
Presented at Stevia World Americas 2010, Atlanta, GA, February 2010
Certified Spiking Solutions® of Immunosuppressant Drugs
Authors: Uma Sreenivasan, Isil Dilek, Sandra Ybarra, Huahua Jian, Mitzi Rettinger
Presented at Mass Spectrometry Application to the Clinical Lab (MSACL), San Diego, February 2010
A Validated Chiral HPLC Method for Resolution of Δ8 and Δ9 – Tetrahydrocannabinol Enantiomers
Authors: Tamara Tarbox, Isil Dilek PhD, Uma Sreenivasan PhD, Kenan Yaser
Presented at EAS, November 2009
Validation of Residual Solvent Analysis in Neat Materials by GC/FID Headspace
Authors: Ning Chang PhD, Krystal Silva, Huahua Jian PhD, Isil Dilek PhD, Uma Sreenivasan PhD
Presented at EAS, November 2009
Synthesis of 13C6-glucuronic Acid Drug Metabolites
Authors: Alexander Wong PhD, Peech Reddy PhD, Martha Liu PhD
Presented at AAPS, November 2009
Brominated Oxymorphone Impurities: Regioselective Synthesis & Characterization of 1-Bromo- & 2-Bromoxymorphone
Authors: Elizabeth Marek PhD, Gregory Kirkovits PhD, Huahua Jian PhD, Uma Sreenivasan PhD
Presented at AAPS, November 2009
An Investigation of Norpropoxyphene Cyclization in Methanol
Authors: Huahua Jian PhD, Sandra Ybarra, Derrell Johnson MS, Isil Dilek PhD and Uma Sreenivasan PhD
Presented at SOFT, October 2009
Preparation and Uncertainty of Ethanol Standards
Authors: Ning Chang PhD, Isil Dilek PhD, Bryan Dockery, Kevin Gates, Huahua Jian PhD, Mitzi Rettinger, Krystal Silva, Uma Sreenivasan PhD
Presented at SOFT, October 2009
Certified Solution Standards for Clinical Applications
Authors: Isil Dilek PhD, Kevin Gates, Rebecca Johnson, Sherri Pogue, Mitzi Rettinger, Uma Sreenivasan PhD
Presented at TIAFT, August 2009
Preparation, Uncertainty & Certification of Ethanol Standards
Authors: Ning Change PhD, Isil Dilek PhD, Bryan Dockery, Kevin Gates, Huahua Jian PhD, Mitzi Rettinger, Krystal Silva, Uma Sreenivasan PhD
Presented at TIAFT, August 2009
Synthesis of CHMPA-D
Authors: Peech Reddy PhD, Huahua Jian PhD, Isil Dilek PhD, Ryan Carrell, Ning Chang PhD, Uma Sreenivasan PhD
Presented at NMEC, August 2009
Pharmaceutical Standards for Drinking Water Analysis
Authors: Derrell Johnson, Uma Sreenivasan PhD, Kevin Gates, Ning Chang PhD, Isil Dilek PhD, Huahua Jian PhD, Mitzi Rettinger
Presented at NMEC, August 2009
The Uncertainty of Reference Standards - A Guide to Understanding Factors Impacting Uncertainty, Uncertainty Calculations and Vendor Certifications
Authors: Ning Chang PhD, Isil Dilek PhD, Kevin Gates, Huahua Jian PhD, Sherri Pogue, Uma Sreenivasan PhD
Presented at SAT, May 2009
Certified Solution Standards for Therapeutic Drug Monitoring Applications
Authors: Isil Dilek PhD, Kevin Gates, Rebecca Johnson, Sherri Pogue, Mitzi Rettinger, Uma Sreenivasan PhD
Presented at SAT, May 2009
Presented at MATT, April 2009



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