Accelerated Stability Studies by HPLC

Accelerated Stability Studies by High Performance Liquid Chromatography

Authors: Greg Serna, Tamara Tarbox, Isil Dilek
Presented at Cerilliant - 2012 Sigma Aldrich® Summer Intern Program, Round Rock, TX, August 2012

Abstract
The purpose of this study was to perform accelerated stability studies to predict the shelf lives of 21 Cerilliant products and compare the results to available real time stability information. From the rates of degradation, an Arrhenius plot was constructed for each product to yield the rate of degradation at the control temperature and the energy of activation for thermolytic degradation. Thermolytic degradation was assumed to be the only decomposition pathway.

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