In the study, mice injected with tumor cells received dosing
of pure CBD and THC together with irradiation. After 21 days the size of tumors
in mice that received combination CBD and THC treatment and irradiation were 7
to 9 fold less in size than tumors in mice that received only radiation
treatment. Tumors of mice exposed to
cannabinoids and irradiation were also found to have lower levels of growth and
vascularization markers than observed in control groups.
The researchers speculate that CBD and THC, as well as other
cannabinoids, improve radiation cancer therapy by interfering with cellular
repair mechanisms. They further speculate that cannabinoids inhibit cancer
development by reducing the growth of new capillary blood vessels. “It is now important to expand this study to
understand the biologic basis of this enhancement, particularly the suggestion
that vascularization may be impeded,” the authors commented.
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