CerilliantLog In | Recently Purchased | Favorites | My COAs | Cart (0)Cerilliant ISO
The Role of Estrogen in Regulating Heart Disease Risk Factors
A November 13th article on the science news site, ScienceDaily, highlights the findings of a study suggesting that the hormone estrogen regulates key risk factors associated with heart disease and stroke. The study is published in the journal Arteriosclerosis, Thrombosis and Vascular Biology (Estrogen's role in regulating common health disease risks identified).
 
Scientists from the Schulich School of Medicine & Dentistry's Robarts Research Institute, in Canada, showed that estrogen can activate a protein complex called GPER. Once GPER is activated, a protein known as PCSK-9 is inhibited, which in turn lowers LDL cholesterol. The study also found that women who carry a variant of the GPER gene have significant increases in LDL cholesterol levels. This gene variant was found in 20% of the experimental population comprised of women from northern Alberta and Ontario.
 
According to Dr. Feldman, one of the study’s authors, these findings build upon a previous study his team conducted which concluded that GPER activity could influence blood pressure. He commented that the group’s latest discovery of the gene’s impact on cholesterol levels increases the importance of determining whether a woman has altered GPER activity.
 
Cerilliant provides Certified Spiking Solutions® for a wide variety of hormones monitored by LC-MS/MS in pregnancy or female health such as estradiol, progesterone, estriol, estrone, and 17α-ethynylestradiol. These certified solutions are suitable for MS-based testing methods in current and emerging critical applications including cancer testing, neonatal screening, biomarker research, hormone replacement therapy, and clinical chemistry.
 
Cerilliant reference solutions are produced and certified to the highest industry standards including ISO 13485, ISO Guide 34, and ISO/IEC 17025 and are classified as "certified reference materials" in accordance with ISO requirements. Click on the link below to view Cerilliant Certified Spiking Solutions® of female hormones:
 
 
 


Return to Article List


© 2018 Cerilliant Corporation | 811 Paloma Drive, Suite A | Round Rock, Texas 78665
Sigma-Aldrich is a subsidiary of Merck KGaA, Darmstadt, Germany
Products | News/Events | Sitemap | Privacy Policy | EHS Policy | Terms & Conditions | Contact
Follow Us: Cerilliant Linkedin LinkedIn