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17-August-2010
Cerilliant Introduces New Certified Spiking Solution® for Methotrexate

Methotrexate, 1.0 mg/mL M-136
1.0 mg/mL in Methanol with 0.1N NaOH

A Certified Spiking Solution® for use in therapeutic drug monitoring (TDM) analyses by HPLC or LC/MS. Used in the treatment of cancer and autoimmune diseases, methotrexate is an antimetabolite and antifolate drug monitored by clinical labs to ensure patients remain within the drug’s therapeutic range. The Snap-N-Spike® format allows laboratories to eliminate weighing operations of hazardous substances such as methotrexate, significantly reducing occupational exposure hazards related to handling of acutely toxic powders, and provides the ability to spike into their matrix of choice just before use.

In addition to other anti-cancer drugs such as paclitaxel (P-065), we offer Certified Spiking Solutions® of numerous TDM drugs and Narrow Therapeutic Index/NTI drugs including amiodarone, cyclosporin A, disopyramide, ethosuximide, mycophenolic acid, sirolimus, and tacrolimus.


Cerilliant Certified Solution Standards and Certified Spiking Solutions are manufactured to the highest industry standards. We are accredited to ISO Guide 34 and ISO/IEC 17025 & certified to ISO 13485 and ISO 9001. Our quality system also incorporates cGMP and GLP requirements


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