Cerilliant operates a state of the art synthesis laboratory to support its catalog product offering as well as production of custom materials for clients. Cerilliant employs a diverse team of highly credentialed chemists, most with advanced degrees, in its in-house synthesis department. This diversity of backgrounds and extensive experience puts Cerilliant in a unique position to serve its customers’ needs. Cerilliant chemists are versed in a broad range of organic synthetic techniques and multi-step syntheses with capabilities in the mg to kilo-scale (large scale synthesis using up to 100L reactors).

Cerilliant synthesizes in-house approximately 60% of the materials utilized in its catalog offering including a wide variety of drugs of abuse, pharmaceutical substances, metabolites, intermediates, impurities, degradants, difficult to find environmental materials, polycyclic aromatic hydrocarbons, pesticides, dioxins and furans, chemical warfare agents, explosives, and stable isotope labeled materials. In-house manufacture allows Cerilliant to better control the quality of its products, achieve higher levels of purity, and offer clients a one-stop shop for reference material needs.

Our synthesis expertise includes:

• Synthesis of high purity reference materials
• Design, synthesis and isolation of drug impurities, metabolites, glucuronides
• Controlled substances C I-V
• Heterocyclic chemistry – pharmaceuticals, forensics
• Opiate chemistry
• Cannabinoids
• Synthesis of stable isotope labeled materials (e.g. deuterium, ¹³C, ¹⁵N)
• Environmental chemistry - polycyclic aromatic hydrocarbons, pesticides, dioxins/furans
• Highly reactive/explosive substances (ATFE licensed as manufacturer of High Explosives)
• Chiral syntheses and separations
• Distillations
• Hydrogenations
• Isolation of active materials by extraction from tablets/capsules
• Handling of light sensitive, toxic, or highly hazardous materials in isolation suites
• Purification of purchased materials to reach desired specifications
• Preparative chromatography for difficult separations, normal and reverse phase
• Thorough analytical characterization and documentation of work