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News Article Highlights Long-Term Health Effects of Benzodiazepines
An article in the June 30, 2009, on-line edition of The Washington Post highlighted the long-term health effects of benzodiazepines. Benzodiazepines are often prescribed to manage anxiety, panic, and sleep disorders and in connection with pain management regimens. Originally pushed as an alternative to barbiturates, their use has grown rapidly over the last 30 years. Health officials and consumers have increasingly noted the potential for physical dependence and grueling withdrawals after taking the drugs for more than a few weeks (The Washington Post).

The article indicated that 85 million prescriptions were filled in 2008 for the top 20 benzodiazepines, an increase of 10 million over the number of prescriptions filled in 2004. Critics argue that benzodiazepines are over-prescribed and can produce serious side effects. According to health experts, some patients require high doses after a few years in order to receive the same effect due to drug tolerance. The article provided estimates which showed that 10 to 20 percent of patients taking benzodiazepines will experience problems with dose escalation and physical dependence.

Patients who overcame the withdrawal effects of benzodiazepines reported the ordeal as rivaling the withdrawals from ending a heroin habit. According to experts, potential adverse events from benzodiazepine withdrawals include hallucinations, seizures, and even death.

The article reported that some doctors have turned to selective serotonin reuptake inhibitors (SSRIs), which include antidepressants, to replace benzodiazepines in the treatment of anxiety. Doctors such as Steven Daviss, chairman of psychiatry at the Baltimore Washington Medical Center, believe SSRIs are a safer alternative than benzodiazepines with less risk for dependence and a less dangerous withdrawal.

Cerilliant provides certified solution standards for a wide variety of native and labeled benzodiazepines and their metabolites. Cerilliant also offers certified solution standards of numerous tricyclic, tetracyclic, and SSRI antidepressants as well as their internal standards and metabolites. We provide the widest selection and highest quality isotope labeled and “native” solution standards suitable for a number of uses, including forensic toxicology, clinical or pharmaceutical analysis, urine drug testing, urine prescription monitoring, calibrator preparation, and isotope dilution methods. Click on the links below to view these featured certified reference standards:

Cerilliant Certified Drug Standards of Benzodiazepines
Cerilliant Certified Drug Standards of Tricyclic Antidepressants
Cerilliant Certified Drug Standards of Tetracyclic Antidepressants
Cerilliant Certified Drug Standards of SSRI Antidepressants

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